Edit |   |
---|---|
Antigenic Specificity | MAX(Phospho-Ser11) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of MAX only when phosphorylated at serine 11. Members of the Myc/Max/Mad network function as transcriptional regulators with roles in various aspects of cell behavior including proliferation, differentiation and apoptosis (1). These proteins share a common basic-helix-loop-helix leucine zipper (bHLH-ZIP) motif required for dimerization and DNA-binding. Max was originally discovered based on its ability to associate with c-Myc and found to be required for the ability of Myc to bind DNA and activate transcription (2). Subsequently, Max has been viewed as a central component of the transcriptional network, forming homodimers as well as heterodimers with other members of the Myc and Mad families (1). The as |
Immunogen | Immunogen Type: Peptide Immunogen Description: A phospho specific peptide corresponding to residues surrounding S11 of human MAX. |
Other Names | [MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; orf1] |
Gene, Accession # | [MAX], Gene ID: 4149, NCBI: NP_001257997.1, UniProt: P61244 |
Catalog # | MBS9412489 |
Price | $320 |
Order / More Info | MAX(Phospho-Ser11) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |