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Antigenic Specificity | HUWE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.8mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. |
Immunogen | Immunogen: Synthetic peptide of human HUWE1 |
Other Names | [ARF binding protein 1; ARF BP1; ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin protein ligase HUWE1; E3 ubiquitin-protein ligase HUWE1; HECT; HECT domain protein LASU1; HECT UBA and WWE domain containing protein 1; HectH9; Homologous to E6AP carboxyl terminus homologous protein 9; Huwe1; HUWE1; Ib772; Large structure of UREB1; LASU1; Mcl 1 ubiquitin ligase E3; Mcl-1 ubiquitin ligase E3; Mule; UBA and WWE domain-containing protein 1; Upstream regulatory element-binding protein 1; URE-B1; URE-binding protein 1; UREB1] |
Gene, Accession # | [HUWE1], Gene ID: 10075, NCBI: NP_113584, UniProt: Q7Z6Z7 |
Catalog # | MBS2561429 |
Price | $110, $150, $225 |
Order / More Info | HUWE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |