MMP2/Collagenase Type IV A (Tumor Metastasis Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMMP2/Collagenase Type IV A (Tumor Metastasis Marker)
Clone[MMP2/1501]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
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DescriptionSpecificity: It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
ImmunogenImmunogen: Recombinant human MMP2 protein fragment (aa444-575) Cellular Localization: Cytoplasmic and Cell Surface
Other Names[72kD type IV collagenase; CLG4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase A; Gelatinase alpha; Gelatinase neutrophil; Matrix metalloproteinase-2; MMP2; MONA; Neutrophil gelatinase; PEX; TBE-1]
Gene, Accession #[MMP2], Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253
Catalog #MBS4380110
Price$190, $340, $340
Order / More InfoMMP2/Collagenase Type IV A (Tumor Metastasis Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHuhtala, P., et al. 1990. Structure of the human type IV collagenase gene. J. Biol. Chem. 265: 11077-11082.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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