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Antigenic Specificity | MMP2/Collagenase Type IV A (Tumor Metastasis Marker) |
Clone | [MMP2/1501] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. |
Immunogen | Immunogen: Recombinant human MMP2 protein fragment (aa444-575) Cellular Localization: Cytoplasmic and Cell Surface |
Other Names | [72kD type IV collagenase; CLG4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase A; Gelatinase alpha; Gelatinase neutrophil; Matrix metalloproteinase-2; MMP2; MONA; Neutrophil gelatinase; PEX; TBE-1] |
Gene, Accession # | [MMP2], Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253 |
Catalog # | MBS4380110 |
Price | $190, $340, $340 |
Order / More Info | MMP2/Collagenase Type IV A (Tumor Metastasis Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Huhtala, P., et al. 1990. Structure of the human type IV collagenase gene. J. Biol. Chem. 265: 11077-11082. |