CREB3L1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCREB3L1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionTranscription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in bone formation through the transcription of COL1A1, and possibly COL1A2, and the secretion of bone matrix proteins. Directly binds to the UPR element (UPRE)-like sequence in an osteoblast-spec
ImmunogenImmunogen: Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 1 protein (396-500AA)
Other Names[Cyclic AMP-responsive element-binding protein 3-like protein 1; cAMP-responsive element-binding protein 3-like protein 1; Old astrocyte specifically-induced substance; OASIS; Processed cyclic AMP-responsive element-binding protein 3-like protein 1; CREB3L1; OASIS; PSEC0238]
Gene, Accession #[CREB3L1], Gene ID: 90993, NCBI: NP_443086.1, UniProt: Q96BA8
Catalog #MBS7051024
Price$160, $235
Order / More InfoCREB3L1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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