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Antigenic Specificity | DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE) |
Clone | [7H31] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein G purified |
Size | 100 tests |
Concentration | 0.025mg/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Species sequence homology: mouse - 60%. Recognizes human DARC. Stains human DARC transfected cells but not irrelevant transfectants. DARC, also known as Duffy antigen, Fy glycoprotein, and CD234, is a 7TM non-signaling chemokine receptor that is expressed on venular endothelial cells and erythrocytes. DARC binds and mediates the internalization of several inflammatory CC and CXC chemokines. It transports chemokines to the lumenal face of venular endothelium to promote the extravasation of leukocytes to sites of inflammation. DARC polymorphisms are important in blood transfusion compatibility and determine the susceptibility of erythrocytes to Plasmodium vivax infection. |
Immunogen | Immunogen: HEK293 cells transfected with human DARC, Accession # CAA59770 |
Other Names | [-DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE)], [DARC; DARC; FY; Dfy; GPD; GpFy; ACKR1; CCBP1; CD234; WBCQ1; FY; GPD; GpFy] |
Gene, Accession # | Gene ID: 2532, NCBI: NP_001116423.1, UniProt: Q16570 |
Catalog # | MBS603510 |
Price | $695 |
Order / More Info | DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |