DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE)
Clone[7H31]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
FormatProtein G purified
Size100 tests
Concentration0.025mg/ml
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionSpecificity: Species sequence homology: mouse - 60%. Recognizes human DARC. Stains human DARC transfected cells but not irrelevant transfectants. DARC, also known as Duffy antigen, Fy glycoprotein, and CD234, is a 7TM non-signaling chemokine receptor that is expressed on venular endothelial cells and erythrocytes. DARC binds and mediates the internalization of several inflammatory CC and CXC chemokines. It transports chemokines to the lumenal face of venular endothelium to promote the extravasation of leukocytes to sites of inflammation. DARC polymorphisms are important in blood transfusion compatibility and determine the susceptibility of erythrocytes to Plasmodium vivax infection.
ImmunogenImmunogen: HEK293 cells transfected with human DARC, Accession # CAA59770
Other Names[-DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE)], [DARC; DARC; FY; Dfy; GPD; GpFy; ACKR1; CCBP1; CD234; WBCQ1; FY; GPD; GpFy]
Gene, Accession #Gene ID: 2532, NCBI: NP_001116423.1, UniProt: Q16570
Catalog #MBS603510
Price$695
Order / More InfoDARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (PE) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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