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Antigenic Specificity | HSF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HSF1 antibody detects endogenous levels of total HSF1. Description: HSF1 a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of HSF1. Two alternatively spliced isoforms have been described.Function: Function as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults' damage (PubMed:1871105, PubMed:11447121, PubMed:1986252, PubMed:7760831, PubMed:7623826 |
Immunogen | Immunogen: A synthesized peptide derived from human HSF1 Subcellular Location: Cytoplasm. Nucleus. Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules. |
Other Names | [Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; hsf1; HSF1_HUMAN; HSTF 1; HSTF1] |
Gene, Accession # | [HSF1], Gene ID: 3297, NCBI: NP_005517.1, UniProt: Q00613 |
Catalog # | MBS9600045 |
Price | $240, $280 |
Order / More Info | HSF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |