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Antigenic Specificity | CD54/ICAM-1 |
Clone | [15.2] |
Host Species | Mouse |
Reactive Species | human, porcine |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. |
Immunogen | Immunogen: Human monocytes. |
Other Names | [CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells] |
Gene, Accession # | [ICAM1], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362 |
Catalog # | MBS4380988 |
Price | $190, $340, $340 |
Order / More Info | CD54/ICAM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hromatka, BS et al. Biol Reprod. 2013 Jun 20;88(6):154. (IHC) 2. Huegel R et al. J Invest Dermatol. 2007 Jan;127(1):65-74. (IC) 3. Johnson, J.P., et al. Leucocyte Typing IV, Oxford Univ. Press, pp 681-683. (FC) |