CD54/ICAM-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD54/ICAM-1
Clone[15.2]
Host SpeciesMouse
Reactive Specieshuman, porcine
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionRecognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
ImmunogenImmunogen: Human monocytes.
Other Names[CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells]
Gene, Accession #[ICAM1], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362
Catalog #MBS4380988
Price$190, $340, $340
Order / More InfoCD54/ICAM-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hromatka, BS et al. Biol Reprod. 2013 Jun 20;88(6):154. (IHC) 2. Huegel R et al. J Invest Dermatol. 2007 Jan;127(1):65-74. (IC) 3. Johnson, J.P., et al. Leucocyte Typing IV, Oxford Univ. Press, pp 681-683. (FC)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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