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Antigenic Specificity | Connexin 32 (Gap Junction Protein) |
Clone | [M12.13] |
Host Species | Mouse |
Reactive Species | human, mouse, rat. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully sub |
Immunogen | Immunogen: Rat junctional complexes. Cellular Localization: Cytoplasmic and Cell Surface |
Other Names | [Charcot Marie Tooth neuropathy X linked; CMTX; CMTX1; Connexin-32; Cx32; GAP junction 28kDa liver protein; Gap junction beta-1 protein; Gap junction protein beta 1 32kD; GJB1], [GJB1; GJB1; CMTX; CX32; CMTX1; CX32; Cx32] |
Gene, Accession # | [GJB1], Gene ID: 2705, NCBI: NP_000157.1, UniProt: P08034 |
Catalog # | MBS439991 |
Price | $190, $340, $340 |
Order / More Info | Connexin 32 (Gap Junction Protein) Antibody from MYBIOSOURCE INC. |
Product Specific References | D. A. Goodenough et. al. Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions. Journal of Cell Biology, 107(5), 1817-1824 (1988). |