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Antigenic Specificity | Chicken b2-microglobulin |
Clone | [F21-21] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry; Immunoprecipitation; Western Blot; Immunoaffinity Chromatography |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The beta 2-microglobulin subunit (Mr ~ 14 kDa) of avian MHC Class I molecules. Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha -chain (Mr ~ 44 kDa) non-covalently bound to the invariant beta 2-microglobulin subunit (Mr ~ 14 kDa). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-2 MAb F21-21 also reacts with turkey beta 2-microglobulin.3. |
Immunogen | n/a |
Other Names | [Mouse Chicken b2-microglobulin - Purified, Unlabeled; Mouse Chicken beta 2-Microglobulin], [B2M; B2M; B2M] |
Gene, Accession # | Gene ID: 567, UniProt: P61769 |
Catalog # | MBS673936 |
Price | $305 |
Order / More Info | Chicken b2-microglobulin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Skjodt, K., K.G. Welinder, M.Crone, S. Verland, J. Salomonsen, and M. Simonsen. 1986. Mol. Immunol. 23:1301-1309.2. Dunon, D., J. Kaufman, J. Salomonsen, K. Skjodt, O. Vainio, J.P. Thiery, and B.A. Imhof. 1990. EMBO J. 9:3315-3322.4. Salomonsen, J. Personal communication. |