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Antigenic Specificity | Kif 7 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous Kif 7 proteins. KIF7 encodes a cilia-associated protein (kinesin family member 7) belonging to the kinesin family. Kinesin family member 7 plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in KIF7 have been associated with various ciliopathies. |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse Kif 7] |
Gene, Accession # | [Kif 7], Gene ID: 374654, NCBI: NP_940927.2, UniProt: Q2M1P5 |
Catalog # | MBS9700362 |
Price | $130, $220, $325 |
Order / More Info | Kif 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |