LMNB1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-LMNB1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | LMNB1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Lamins are nuclear membrane structural components that are important in maintaining normal cell functions, such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamins have been subdivided into types A and B. Type-A lamins consist of lamin A and C, arising from alternative splicing. Lamin A and C are cleaved by caspases into large (41-50 kDa) and small (28 kDa) fragments, which can be used as markers for apoptosis (4, 5). Type-B lamins consist of lamin B1 and B2, encoded by separate genes (6-8). Lamin B1 is also cleaved by caspases during apoptosis (9). Research studies have shown that duplication of the lamin B1 gene is correlated with the pathogenesis of the neurological disorder adult-onset leukodystrophy (10). |
| Immunogen | Immunogen: Fusion protein of human LMNB1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [ADLD; LMN; LMN2; LMNB; MGC111419; Lamin B1] |
| Gene, Accession # | [LMNB1], Gene ID: 4001, NCBI: NP_005564.1, UniProt: P20700 |
| Catalog # | MBS8527397 |
| Price | $310 |
| Order / More Info | LMNB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gruenbaum, Y. et al. (2000) J Struct Biol 129, 313-23. 2. Goldberg, M. et al. (1999) Crit Rev Eukaryot Gene Expr 9, 285-93. 3. Yabuki, M. et al. (1999) Physiol Chem Phys Med NMR 31, 77-84. 4. Rao, L. et al. (1996) J Cell Biol 135, 1441-55. 5. Orth, K. et al. (1996) J Biol Chem 271, 16443-6. 6. Biamonti, G. et al. (1992) Mol Cell Biol 12, 3499-506. 7. Lin, F. and Worman, H.J. (1995) Genomics 27, 230-6. 8. Pollard, K.M. et al. (1990) Mol Cell Biol 10, 2164-75. 9. Chandler, J.M. et al. (1997) Biochem J 322 (Pt 1), 19-23. 10. Padiath, Q.S. et al. (2006) Nat Genet 38, 1114-23. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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