NO66 (652) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NO66 (652) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mL, 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FC/FACS), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7, OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7, OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human NO66 |
| Other Names | [NO66(652) Mouse mAb; 60S ribosomal protein L8 histidine hydroxylase; Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Histone lysine demethylase NO66; hsNO66; lysine-specific demethylase NO66; MAPJD; MYC-associated protein with JmjC domain; NO66; Nucleolar protein 66; Ribosomal oxygenase 1; Ribosomal oxygenase NO66; ROX; up-regulated in lung cancer 2; C14orf169; hsNO66; MAPJD; NO66; RIOX1; ROX; URLC2], [RIOX1; RIOX1; ROX; NO66; JMJD9; MAPJD; URLC2; hsNO66; C14orf169; C14orf169; MAPJD; NO66; hsNO66; ROX] |
| Gene, Accession # | [NO66], Gene ID: 79697, NCBI: NP_078920.2, UniProt: Q9H6W3 |
| Catalog # | MBS435174 |
| Price | $225, $350, $565 |
| Order / More Info | NO66 (652) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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