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Antigenic Specificity | PTP IA-2beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PTP IA-2beta Polyclonal Antibody detects endogenous levels of PTP IA-2beta protein. PTPRN2 (protein tyrosine phosphatase, receptor type N2) encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative spl |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human PTP IA-2beta at AA range: 180-260 |
Other Names | [Rabbit PTP IA-2beta; PTPRN2; KIAA0387; Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; Islet cell autoantigen-related protein; IAR; ICAAR; Phogrin] |
Gene, Accession # | [PTP IA-2beta], Gene ID: 5799, NCBI: NP_002838.2, UniProt: Q92932 |
Catalog # | MBS9706571 |
Price | $130, $220, $325 |
Order / More Info | PTP IA-2beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |