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Antigenic Specificity | CCR3 (Center), 291-318 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3. CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. |
Immunogen | n/a |
Other Names | [C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; Eosinophil eotaxin receptor; CD193; CCR3; CMKBR3] |
Gene, Accession # | [CCR3], Gene ID: 1232, NCBI: NP_001828.1, UniProt: P51677 |
Catalog # | MBS9212800 |
Price | $165, $370 |
Order / More Info | CCR3 (Center), 291-318 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ponath,P.D., et.al., J. Clin. Invest. 97 (3), 604-612 (1996) |