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Antigenic Specificity | Phospho-HDAC4/5/9-S246/259/220 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general,they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the class to which t |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S246/259/220 of human HDAC4/5/9 Calculated Molecular Weight: 140; 142kDa |
Other Names | [Phospho-HDAC4/HDAC5/HDAC9-S246/259/220: HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A/HD5; NY-CO-9/HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL], [HDAC4; HDAC4; HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; KIAA0288; HD4] |
Gene, Accession # | [HDAC4/HDAC5/HDAC9], Gene ID: 9759, NCBI: P56524.3, UniProt: P56524 |
Catalog # | MBS128295 |
Price | $235, $350, $525 |
Order / More Info | Phospho-HDAC4/5/9-S246/259/220 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |