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Antigenic Specificity | Human Cell death activator CIDE-3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apop |
Immunogen | Immunogen: Recombinant human Cell death activator CIDE-3 protein (1-238aa) |
Other Names | [Cell death-inducing DFFA-like effector protein C; Fat-specific protein FSP27 homolog; CIDEC; FSP27], [CIDEC; CIDEC; CIDE3; FPLD5; FSP27; CIDE-3; FSP27] |
Gene, Accession # | [CIDEC], Gene ID: 63924, NCBI: NP_001186480.1, UniProt: Q96AQ7 |
Catalog # | MBS1498530 |
Price | $120, $160 |
Order / More Info | Human Cell death activator CIDE-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |