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Antigenic Specificity | Mouse GRN |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on |
Immunogen | Immunogen: Recombinant Mouse Granulin/Progranulin/GRN protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [GRN, partial; Granulins; granulins; granulin precursor; Proepithelin; PEPI] |
Gene, Accession # | [GRN ], Gene ID: 2896 |
Catalog # | MBS2544566 |
Price | $215, $330, $500 |
Order / More Info | Mouse GRN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |