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Antigenic Specificity | PDX-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PDX-1 Polyclonal Antibody detects endogenous levels of PDX-1 protein. The protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Immunogen | Immunogen: Synthesized peptide derived from human PDX-1 around the non-phosphorylation site of S61 |
Other Names | [Rabbit PDX-1; PDX1; IPF1; Pancreas/duodenum homeobox protein 1; PDX-1; Glucose-sensitive factor; GSF; Insulin promoter factor 1; IPF-1; Insulin upstream factor 1; IUF-1; Islet/duodenum homeobox-1; IDX-1; Somatostatin-transactivating factor 1; STF-1] |
Gene, Accession # | [PDX-1], Gene ID: 3651, NCBI: NP_000200.1, UniProt: P52945 |
Catalog # | MBS9705552 |
Price | $130, $220, $325 |
Order / More Info | PDX-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |