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Antigenic Specificity | Pias2 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Pias2. It was validated on Western BlotTarget Description: Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor.Pias2 plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and PIAS2 isoform studied. However, it seems to be mostly involved in gene silencing.Pias2 binds to sumoylated ELK1 and enhances its transcriptional activity by preven |
Immunogen | Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse |
Other Names | [E3 SUMO-protein ligase PIAS2 isoform 1; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein ligase PIAS2; protein inhibitor of activated STAT 2; Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; Msx-interacting zinc finger protein; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2] |
Gene, Accession # | [PIAS2], Gene ID: 17344, NCBI: NP_032628, UniProt: Q8C5D8 |
Catalog # | MBS3203794 |
Price | $335 |
Order / More Info | Pias2 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |