Edit |   |
Antigenic Specificity | RAP2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAP2B antibody detects endogenous levels of total RAP2B. Function: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.Subunit Structure: Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A (By similarity).Post-translational Modifications: Palmitoylated. Unlike RAP2A and RAP2C, palmitoylation of RAP2B is not required for association with recycling endosome membranes and activ |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Recycling Endosome Membrane. Associated with red blood cells-released vesicles. Tissue Specificity: Expressed in red blood cells (at protein level). Predicted Cross Reactivity: Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Zebrafish (92%), Bovine (92%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (100%) |
Other Names | [MGC20484; RAP 2B; RAP2A; Rap2b; RAP2B member of RAS oncogene family; RAP2B_HUMAN; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; Ras related protein RAP2B; Ras-related protein Rap-2b; Small GTP binding protein] |
Gene, Accession # | [RAP2B], Gene ID: 5912, NCBI: NP_002877.2, UniProt: P61225 |
Catalog # | MBS9605864 |
Price | $240, $280 |
Order / More Info | RAP2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |