RAP2B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAP2B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: RAP2B antibody detects endogenous levels of total RAP2B. Function: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.Subunit Structure: Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A (By similarity).Post-translational Modifications: Palmitoylated. Unlike RAP2A and RAP2C, palmitoylation of RAP2B is not required for association with recycling endosome membranes and activ
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Recycling Endosome Membrane. Associated with red blood cells-released vesicles. Tissue Specificity: Expressed in red blood cells (at protein level). Predicted Cross Reactivity: Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Zebrafish (92%), Bovine (92%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (100%)
Other Names[MGC20484; RAP 2B; RAP2A; Rap2b; RAP2B member of RAS oncogene family; RAP2B_HUMAN; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; Ras related protein RAP2B; Ras-related protein Rap-2b; Small GTP binding protein]
Gene, Accession #[RAP2B], Gene ID: 5912, NCBI: NP_002877.2, UniProt: P61225
Catalog #MBS9605864
Price$240, $280
Order / More InfoRAP2B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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