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Antigenic Specificity | Di-Methyl-Histone H3 (Lys27) (3B8) |
Clone | [3B8-7G7-4E5] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous Histone H3 (di methyl K27) protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2). |
Immunogen | Immunogen: Synthetic Peptide of Histone H3 (Di Methyl Lys27) |
Other Names | [H3 histone; HIST1H3A; Histone cluster 1; H3a] |
Gene, Accession # | [HIST3H3], Gene ID: 8350, NCBI: NP_003520.1, UniProt: P68431 |
Catalog # | MBS4751487 |
Price | $335 |
Order / More Info | Di-Methyl-Histone H3 (Lys27) (3B8) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |