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Antigenic Specificity | IFT25 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFT25 antibody detects endogenous levels of IFT25. Function: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly (By similarity).Subunit Structure: Component of the IFT complex B, at least composed of IFT20, IFT22, HSPB11/IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88. Interacts with IFT27; the interaction is direct. Interacts with IFT88 ( |
Immunogen | Immunogen: A synthesized peptide derived from human IFT25. Tissue Specificity: Detected in placenta. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (92%), Horse (92%), Sheep (92%), Rabbit (83%), Dog (92%), Xenopus (82%) |
Other Names | [Chromosome 1 open reading frame 41; Heat shock protein beta-11; HSB11_HUMAN; Hspb11; HSPCO34; IFT25; Placental protein 25; PP25] |
Gene, Accession # | [IFT25], Gene ID: 51668, NCBI: NP_001303864.1, UniProt: Q9Y547 |
Catalog # | MBS9603385 |
Price | $240, $280 |
Order / More Info | IFT25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |