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Antigenic Specificity | Human SMAD3 |
Clone | [2C12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human SMAD3. SMAD3, a transcriptional regulator, is activated by TGF-beta and Activin 1 receptor kinase. SMAD3 recognizes an 8 bp palindromic sequence GTCTAGAC. Upon phosphorylation at two extreme C-terminal serines, SMAD3 is translocated into the nucleus where is forms complexes other SMAD proteins, depending on the activation pathway, and regulates the transcription of target genes. |
Immunogen | Immunogen Description: SMAD3 (NP_005893, 120 a.a. ~ 222 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Other Names | [SMAD3 (clone 2C12) IHC-plus; SMAD3; HSPC193; HMAD-3; HsT17436; LDS1C; LDS3; Mad homolog JV15-2; MAD3; MADH3; Mothers against DPP homolog 3; JV15-2; SMA- and MAD-related protein 3; SMAD family member 3; MAD homolog 3; HSMAD3; Mad protein homolog; SMAD 3; Human SMAD3], [SMAD3; SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436; MADH3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; SMAD 3; Smad3; hSMAD3] |
Gene, Accession # | [SMAD3], Gene ID: 4088, NCBI: NP_005893.1, UniProt: P84022 |
Catalog # | MBS246411 |
Price | $605 |
Order / More Info | Human SMAD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |