RAD51L2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RAD51L2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RAD51L2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RAD51L2 antibody detects endogenous levels of total RAD51L2. Function: Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Part of the RAD21 paralog protein complexes BCDX2 and CX3 which act at different stages of the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 seems to act downstream of BRCA2 recruitment and upstream of RAD51 recruitment; CX3 seems to act downstream of RAD51 recruitment; both complexes bind predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junction of replication forks. The BCDX2 |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Cytoplasm. Cytoplasm > Perinuclear Region. Mitochondrion. DNA damage induces an increase in nuclear levels. Accumulates in DNA damage induced nuclear foci or RAD51C foci which is formed during the S or G2 phase of cell cycle. Accumulation at DNA lesions requires the presence of NBN/NBS1, ATM and RPA. Tissue Specificity: Expressed in a variety of tissues, with highest expression in testis, heart muscle, spleen and prostate. |
| Other Names | [BROVCA3; DNA repair protein RAD51 homolog 3; FANCO; MGC104277; R51H3; RA51C_HUMAN; Rad 51C; RAD51 homolog C (S. cerevisiae); Rad51 homolog c (S. cerevisiae), isoform CRA_b; RAD51 homolog C; RAD51 like protein 2; RAD51 paralog C; RAD51, S. cerevisiae, homolog of, C; RAD51-like protein 2; RAD51C; RAD51C protein; RAD51L2; RAD51L2/RAD51C protein; RGD1563765; Yeast RAD51 homolog 3] |
| Gene, Accession # | [RAD51L2], Gene ID: 5889, NCBI: NP_002867.1, UniProt: O43502 |
| Catalog # | MBS9606098 |
| Price | $240, $280 |
| Order / More Info | RAD51L2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies