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Antigenic Specificity | B7-H4 |
Clone | [ABM53A6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a k |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | B7-H4, a member of B7 family, is a transmembrane protein that has been shown to inhibit T cell responses and neutrophil expansion during bacterial infections. B7-H4 mRNA is widely distributed in mouse and human peripheral tissues and can be induced in monocytes, macrophages, and dendritic cells upon IL-6 and IL-10 stimulation. However, in a variety of tumor cells, B7-H4 is predominantly present in intracellular compartments with unknown mechanism and functions. Cell surface expression of B7-H4 protein is limited and shows an inducible pattern on hematopoietic cells. The overexpression of B7-H4 has been found in various types of human tumors, such as breast cancer, renal cell carcinoma (RCC), ovarian cancer, esophageal squamous cell carcinom |
Immunogen | Immunogen Information: A partial length recombinant protein (a.a 23-220) of B7-H4 was used as the immunogen for this antibody. |
Other Names | [V-set domain-containing T-cell activation inhibitor 1; B7 homolog 4; B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; to B7H4 (Clone: ABM53A6)], [VTCN1; VTCN1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; B7-H4] |
Gene, Accession # | [B7-H4], Gene ID: 79679, NCBI: Q7Z7D3.1, UniProt: Q7Z7D3 |
Catalog # | MBS668282 |
Price | $260 |
Order / More Info | B7-H4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |