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Antigenic Specificity | CST3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CST3 antibody detects endogenous levels of total CST3. Description: Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors (1). Most cell types secrete Cystatin C (1). Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion (2). In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-beta1 signaling (2, 3). Cystatin C may also modulate antigen presentation through its ability to inhibit cathepsins (4). Cystatin C is also a biomarker for kidney dysfunction (5).Function: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiolo |
Immunogen | Immunogen: A synthesized peptide derived from human CST3 Subcellular Location: Secreted. Tissue Specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland. |
Other Names | [AD 8; AD8; Amyloid angiopathy and cerebral hemorrhage; ARMD11; bA218C14.4 (cystatin C); bA218C14.4; Cst 3; Cst3; CST3 protein; Cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; CYTC_HUMAN; Epididymis secretory protein Li 2; Gamma trace; Gamma-trace; HCCAA; HEL S 2; MGC117328; Neuroendocrine basic polypeptide; Post gamma globulin; Post-gamma-globulin] |
Gene, Accession # | [CST3], Gene ID: 1471, NCBI: NP_000090.1, UniProt: P01034 |
Catalog # | MBS9607113 |
Price | $240, $280 |
Order / More Info | CST3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |