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Antigenic Specificity | PRKCZ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. Required for insulin-dependent activation of AKT3, but may function as an adapter rather than a direct activator. Upon insulin treatment may act as a downstream effector of PI3K and contribu |
Immunogen | Immunogen: Recombinant Human Protein kinase C zeta type protein (494-575AA) |
Other Names | [Protein kinase C zeta type; nPKC-zeta; PRKCZ; PKC2] |
Gene, Accession # | [PRKCZ], Gene ID: 5590, NCBI: NP_001028753.1, UniProt: Q05513 |
Catalog # | MBS7049659 |
Price | $160, $235 |
Order / More Info | PRKCZ Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |