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Antigenic Specificity | PHLPP1 (N-term), 531-560 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PHLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the N-terminal region of human PHLPP1. PHLPP1 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. |
Immunogen | n/a |
Other Names | [PH domain leucine-rich repeat-containing protein phosphatase 1; Pleckstrin homology domain-containing family E member 1; PH domain-containing family E member 1; Suprachiasmatic nucleus circadian oscillatory protein; hSCOP; PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP] |
Gene, Accession # | [PHLPP1], Gene ID: 23239, NCBI: NP_919431.2, UniProt: O60346 |
Catalog # | MBS9211781 |
Price | $165, $370 |
Order / More Info | PHLPP1 (N-term), 531-560 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gao,T., J. Biol. Chem. 283 (10), 6300-6311 (2008) Brognard,J., Mol. Cell 25 (6), 917-931 (2007) Gao,T., Mol. Cell 18 (1), 13-24 (2005) |