CD163 (Monocyte & Macrophage Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD163 (Monocyte & Macrophage Marker)
Clone[M130/1210]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin
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DescriptionThis MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identificati
ImmunogenImmunogen: Recombinant human CD163 fragment (around aa 43-196) Cellular Localization: Cell Surface & Cytoplasmic
Other Names[CD163, CD163 antigen, Macrophage-associated antigen, M130, CD163 molecule, Hemoglobin scavenger receptor, MM130; Scavenger receptor cysteine rich type 1 protein M130]
Gene, Accession #[CD163], Gene ID: 9332, NCBI: NP_004235.4, UniProt: Q86VB7
Catalog #MBS4380519
Price$190, $340, $340
Order / More InfoCD163 (Monocyte & Macrophage Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSean K. Lau, Peiguo G. Chu, and Lawrence M. Weiss. CD163: A Specific Marker of Macrophages in Paraffin-Embedded Tissue Samples Am J Clin Pathol 2004; 122:794-801.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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