PINK1 (E417G Mutant) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPINK1 (E417G Mutant)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionDescription: Synthetic peptide derived from a mutant form of the human PINK1 protein Background: Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fl
ImmunogenImmunogen: Synthetic peptide derived from a mutant form of the human PINK1 protein
Other Names[PINK1; PINK1; PINK1], [UNQ740]
Gene, Accession #[PINK1], NCBI: AAQ89316.1
Catalog #MBS396697
Price$340
Order / More InfoPINK1 (E417G Mutant) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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