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Antigenic Specificity | BCR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BRCA1 (Ab-1524) Antibody detects endogenous levels of total BRCA1protein. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have bee |
Immunogen | Immunogen: The antibody was produced against synthesized non-phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1524 (Y-P-SP-Q-E). |
Other Names | n/a |
Gene, Accession # | [BCR] |
Catalog # | MBS417380 |
Price | $405 |
Order / More Info | BCR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |