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Antigenic Specificity | EYA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity). |
Immunogen | Immunogen: Recombinant Human Eyes absent homolog 4 protein (153-224AA) |
Other Names | [Eyes absent homolog 4; EYA4] |
Gene, Accession # | [EYA4], Gene ID: 2070, NCBI: NP_001287941.1, UniProt: O95677 |
Catalog # | MBS7107867 |
Price | $160, $235 |
Order / More Info | EYA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |