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Antigenic Specificity | Tau [pT231] (Tau Protein, Microtubule-associated Protein, MAP) (BSA, Glycerol & Azide Free) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | no preservative |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human Tau. Species sequence homology: mouse and rat. Tau is a neuronal microtubule-associated protein found predominantly on axons and functions to promote tubulin polymerization and stabilize microtubules. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's disease (AD) brain. Hyperphosphorylated Tau is also found in neurofibrillary lesions in a range of other central nervous system disorders. Hyperphosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Numerous serine/threonine kinases inclu |
Immunogen | Immunogen: Synthetic phosphopeptide derived from the region of human tau that contains threonine 231. |
Other Names | [-Tau [pT231] (Tau Protein, Microtubule-associated Protein, MAP) (BSA, Glycerol & Azide Free)], [tau; tau; BcDNA:RE16764; CG12881; CG31057; CG5606; DmelCG31057; dtau] |
Gene, Accession # | Gene ID: 326116, NCBI: NP_651575.1, UniProt: Q9VB13 |
Catalog # | MBS621052 |
Price | $810 |
Order / More Info | Tau [pT231] (Tau Protein, Microtubule-associated Protein, MAP) (BSA, Glycerol & Azide Free) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |