DKK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDKK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionBackground: Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of Dkk1 and Dkk2 inhibited Wnt-3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of Dkk-2, but not that of Dkk-1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 241 of mouse Dkk2 (Internal ID#BV-C52).
Other Names[DKK-2; DKK 2; dkk2; dkk-2; dkk 2; dickkopf homolog-2; dickkopf homolog2; dickkopf homolog 2], [Dkk2; Dkk2; Dickkopf-2; Dkk-2; mDkk-2]
Gene, Accession #[DKK2], Gene ID: 56811, NCBI: NP_064661.2
Catalog #MBS840733
Price$150, $290
Order / More InfoDKK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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