Edit |   |
Antigenic Specificity | Occludin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, porcine |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Occludin antibody detects endogenous levels of total Occludin. Function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.Similarity: The C-terminal is cytoplasmic and is important for interaction with ZO-1. Sufficient for the tight junction localization. Involved in the regulation of the permeability barrier function of the tight junction (By similarity). The first extracellular loop participates in an adhesive interaction. Belongs to the ELL/occludin family. |
Immunogen | Immunogen: A synthesized peptide derived from human Occludin corresponding to a region within the internal amino acids. |
Other Names | [BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; Ocln; OCLN_HUMAN; Tight junction protein occludin] |
Gene, Accession # | [OCLN], Gene ID: 100506658, NCBI: NP_001192183.1, UniProt: Q16625 |
Catalog # | MBS9608114 |
Price | $240, $280 |
Order / More Info | Occludin Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang J, Lu J, Xie X, Xiong J, Huang N, Wei H, Jiang S, Peng J; Journal: Int Immunopharmacol. Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7. Zou Y, Xiang Q, Wang J, Peng J, Wei H; Journal: Biomed Res Int. Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model. Ai XY, Zhang H, Gao SY, Qin Y, Zhong WL, Gu J, Li M, Qiao KL, Tian Q, Cui ZH, Yang JH, Bi Z, Xiao T, Chen S, Liu HJ, Zhou HG, Sun T, Yang C; Journal: Oncotarget. Sesquiterpene binding Gly-Leu-Ser/Lys-co-adaptation pocket to inhibit lung cancer cell epithelial-mesenchymal transition. |