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Antigenic Specificity | Phospho-Histone H3 (Ser10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6,-7 and-9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
Immunogen | Immunogen: Human Phospho-Histone H3(Ser10) synthetic peptide conjugated to KLH. Storage Buffer: PBS (pH 7.4) containing 0.03% Proclin300 and 50% glycerol. |
Other Names | [Histone H3/f; Histone H3; Histone H3/d; Histone H3/b; Histone H3/c; Histone H3/a; Histone H3/l; Histone H3/j; Histone H3/k; Histone H3/h; H3/A; H3FA; Histone H3/i.] |
Gene, Accession # | Gene ID: 8350, NCBI: NP_003520.1, UniProt: P68431 |
Catalog # | MBS8533353 |
Price | $280 |
Order / More Info | Phospho-Histone H3 (Ser10) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |