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Antigenic Specificity | NR1H3 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NR1H3 Antibody detects endogenous levels of total NR1H3. The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been |
Immunogen | Immunogen: Recombinant protein of human NR1H3 |
Other Names | [LXR-a; LXRA; RLD-1] |
Gene, Accession # | [NR1H3], Gene ID: 10062, NCBI: NP_001123573.1, UniProt: Q13133 |
Catalog # | MBS8516334 |
Price | $290 |
Order / More Info | NR1H3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |