Phospho-GATA3 (Ser369) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-GATA3 (Ser369)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-GATA3 (Ser369) Antibody detects endogenous levels of GATA3 only when phosphorylated at Ser369. Description: Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.Subunit Structure: Interacts with TBX21 ('Tyr-530' phosphorylated form).Similarity: Binds DNA via the 2 GATA-type zinc fingers. Each zinc finger may bind either adjacent sites in a palindromic motif, or a different DNA molecule allowing looping and long-range gene regulation. The YxKxHxxxRP motif is critical for DNA-binding and function.
ImmunogenImmunogen: A synthesized peptide derived from human GATA3 around the phosphorylation site of Ser369. Tissue Specificity: T-cells and endothelial cells.
Other Names[GATA 3; GATA binding factor 3; GATA binding protein 3; GATA-binding factor 3; Gata3; GATA3_HUMAN; HDR; HDRS; MGC2346; MGC5199; MGC5445; Trans acting T cell specific transcription factor GATA 3; Trans-acting T-cell-specific transcription factor GATA-3]
Gene, Accession #[GATA3], Gene ID: 2625, NCBI: NP_001002295.1, UniProt: P23771
Catalog #MBS9610633
Price$225, $280, $340
Order / More InfoPhospho-GATA3 (Ser369) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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