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Antigenic Specificity | Phospho-GATA3 (Ser369) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GATA3 (Ser369) Antibody detects endogenous levels of GATA3 only when phosphorylated at Ser369. Description: Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.Subunit Structure: Interacts with TBX21 ('Tyr-530' phosphorylated form).Similarity: Binds DNA via the 2 GATA-type zinc fingers. Each zinc finger may bind either adjacent sites in a palindromic motif, or a different DNA molecule allowing looping and long-range gene regulation. The YxKxHxxxRP motif is critical for DNA-binding and function. |
Immunogen | Immunogen: A synthesized peptide derived from human GATA3 around the phosphorylation site of Ser369. Tissue Specificity: T-cells and endothelial cells. |
Other Names | [GATA 3; GATA binding factor 3; GATA binding protein 3; GATA-binding factor 3; Gata3; GATA3_HUMAN; HDR; HDRS; MGC2346; MGC5199; MGC5445; Trans acting T cell specific transcription factor GATA 3; Trans-acting T-cell-specific transcription factor GATA-3] |
Gene, Accession # | [GATA3], Gene ID: 2625, NCBI: NP_001002295.1, UniProt: P23771 |
Catalog # | MBS9610633 |
Price | $225, $280, $340 |
Order / More Info | Phospho-GATA3 (Ser369) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |