BCL10 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BCL10 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | 1ug/ul |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bcl-10 is a 31kDa protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
| Immunogen | Immunogen: Ni-NTA purified recombinant human BCL-10 expressed in E Coli strain BL21 (DE3). |
| Other Names | [B-cell lymphoma/leukemia 10 isoform 2; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10], [BCL10; BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10] |
| Gene, Accession # | [BCL10], Gene ID: 8915, NCBI: NP_001307644.1 |
| Catalog # | MBS418365 |
| Price | $445 |
| Order / More Info | BCL10 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Willis, T.G., et al. (1999) Cell. 96, 35-45. 2.Lucas, P.C., et al. (2001) J. Biol.Chem. 276, 19012-19019. 3.Wang, L., et al. (2001) J. Biol.Chem. 276, 21405-21409 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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