DNA polymerase eta Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNA polymerase eta
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatbiotin conjugate
Size0.1 mg
Concentration0.70-0.98 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionBIOTIN-Conjugated Chain B, Yeast DNA polymerase Eta Antibody. DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7, 8-dihydro-8-oxoguanine, 2, 6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta. Expression: Induced by UV radiation and heat shock. The mRNA is stabilized during stationary phase.
Other Names[DNA polymerase eta; FLJ16395; FLJ21978; POLH; polymerase DNA directed eta; RAD30; RAD30 homolog A; Xeroderma pigmentosum variant type protein; XPV], [RAD30; DBH1]
Gene, Accession #UniProt: Q04049
Catalog #MBS544681
Price$495
Order / More InfoDNA polymerase eta Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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