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Antigenic Specificity | DNA polymerase eta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.70-0.98 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BIOTIN-Conjugated Chain B, Yeast DNA polymerase Eta Antibody. DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7, 8-dihydro-8-oxoguanine, 2, 6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta. Expression: Induced by UV radiation and heat shock. The mRNA is stabilized during stationary phase. |
Other Names | [DNA polymerase eta; FLJ16395; FLJ21978; POLH; polymerase DNA directed eta; RAD30; RAD30 homolog A; Xeroderma pigmentosum variant type protein; XPV], [RAD30; DBH1] |
Gene, Accession # | UniProt: Q04049 |
Catalog # | MBS544681 |
Price | $495 |
Order / More Info | DNA polymerase eta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |