ROR2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ROR2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ROR2 antibody detects endogenous levels of total ROR2. Function: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).Subunit Structure: Homodimer; promotes osteogenesis. Binds YWHAB (PubMed:17717073). Interacts with WTIP (By similarity).Similarity: Belongs to the protein kinase superfamil |
| Immunogen | Immunogen: A synthesized peptide derived from human ROR2 Subcellular Location: Plasma Membrane Tissue Specificity: Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. |
| Other Names | [BDB; BDB1; Brachydactyly type B; EC 2.7.10.1; MGC163394; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase, receptor related 2; NTRKR2; Receptor tyrosine kinase-like orphan receptor 2; receptor-related 2; ROR2; ROR2_HUMAN; Tyrosine protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase transmembrane receptor Ror2] |
| Gene, Accession # | [ROR2], Gene ID: 4920, NCBI: NP_001305133.1, UniProt: Q01974 |
| Catalog # | MBS9608433 |
| Price | $240, $280 |
| Order / More Info | ROR2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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