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Antigenic Specificity | DES |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments and microtubules. Major types of intermediate filaments are distinguished and expressed in particular cell types: cytokeratins (epithelial cells), glial fibrillary acidic protein or GFAP (glial cells), desmin (skeletal, visceral and certain vascular smooth muscle cells), vimentin (mesenchyme origin) and neurofilaments (neurons). GFAP and vimentin form intermediate filaments in astroglial cells and modulate their motility and shape (1). In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. Thus, GFAP is commonly used |
Immunogen | Immunogen: Recombinant protein of human DES Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [DES; CMD1I; CSM1; CSM2; FLJ12025; FLJ39719; FLJ41013; FLJ41793] |
Gene, Accession # | [DES], Gene ID: 1674, NCBI: NP_001918.3, UniProt: P17661 |
Catalog # | MBS8504284 |
Price | $310 |
Order / More Info | DES Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Eng, L.F. et al. (2000) Neurochem Res 25, 1439-51. 2. Goebel, H.H. et al. (1987) Acta Histochem Suppl 34, 81-93. 3. Leader, M. et al. (1987) Histopathology 11, 63-72. 4. Capetanaki, Y. et al. (2007) Exp Cell Res 313, 2063-76. 5. Li, Z. et al. (1996) Dev Biol 175, 362-6. 6. Paulin, D. and Li, Z. (2004) Exp Cell Res 301, 1-7. 7. Paulin, D. et al. (2004) J Pathol 204, 418-27. |