Edit |   |
---|---|
Antigenic Specificity | RPS3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also s |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human RPS3 (NP 000996.2). |
Other Names | [S3] |
Gene, Accession # | [RPS3], Gene ID: 6188, NCBI: NP_000996.2, UniProt: P23396 |
Catalog # | MBS8549089 |
Price | $280 |
Order / More Info | RPS3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |