Paxillin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPaxillin
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, rat, mouse, chicken
IsotypeIgG1
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot, Immunocytochemistry, Immunoprecipitation
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DescriptionThis antibody detects a 68kDa* protein corresponding to the molecular mass of paxillin on SDS-PAGE immunoblots of A431 cells. Similar results were seen in various cells and tissues from rat, mouse, and chicken origin. Paxillin, a focal adhesion protein, is involved in focal adhesion formation during cell adhesion and migration. Paxillin contains LD motifs, LIM domains, and SH3-/SH2-binding domains that participate in a variety of protein-protein interactions with kinases, GTPase-activating proteins, and cytoskeletal proteins. Phosphorylation of paxillin occurs at both tyrosine and serine sites. Serine phosphorylation of paxillin occurs in response to growth-factor activation and fibronectins. Both JNK1 and cdc2 kinases can phosphorylate ser
ImmunogenImmunogen: Clone (M107) was generated from full-length recombinant human paxillin.
Other Names[Paxillin; Paxillin], [Pxn; Pxn; Pxn]
Gene, Accession #Gene ID: 360820, NCBI: NP_001012147.1, UniProt: Q66H76
Catalog #MBS470022
Price$325
Order / More InfoPaxillin Antibody from MYBIOSOURCE INC.
Product Specific References• Huang, C. et al. (2003) Nature 424:219-223.• Huang, C. et al. (2004) Cell Cycle 3(1):4-6.• Woodrow, M.A. (2003) Exp. Cell. Res. 287(2):325-338.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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