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Antigenic Specificity | IGF2R (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222; IGF2R; MPRI] |
Gene, Accession # | [IGF2R], Gene ID: 3482, NCBI: NP_000867.2, UniProt: P11717 |
Catalog # | MBS9216992 |
Price | $150 |
Order / More Info | IGF2R (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Morgan D.O.,et al.Nature 329:301-307(1987). Oshima A.,et al.J. Biol. Chem. 263:2553-2562(1988). Gemma A.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. Killian J.K.,et al.Mamm. Genome 10:74-77(1999). Mungall A.J.,et al.Nature 425:805-811(2003). |