CD42c Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD42c
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPlatelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plate
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 56 and 118 of Human GP1BB
Other Names[platelet glycoprotein Ib beta chain; Platelet glycoprotein Ib beta chain; platelet glycoprotein Ib beta chain; glycoprotein Ib (platelet), beta polypeptide; Antigen CD42b-beta; CD_antigen: CD42c]
Gene, Accession #[CD42c], Gene ID: 2812, NCBI: NP_000398
Catalog #MBS9404318
Price$320
Order / More InfoCD42c Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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