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Antigenic Specificity | TNR21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of TNR21 protein. TNFRSF21 encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that TNFRSF21 plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human TNR21 protein at amino acid sequence of 430-510 |
Other Names | [Rabbit TNR21; Death receptor 6; CD_antigen: CD358] |
Gene, Accession # | [TNR21], Gene ID: 27242, NCBI: O75509.1, UniProt: O75509 |
Catalog # | MBS9711250 |
Price | $130, $220, $325 |
Order / More Info | TNR21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |