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Antigenic Specificity | Phospho-PRAK (Thr182) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Immunogen | Immunogen: Synthesized peptide derived from human PRAK around the phosphorylation site of Thr182 Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated |
Other Names | [MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK] |
Gene, Accession # | [PRAK], Gene ID: 8550, NCBI: NP_003659.2, UniProt: Q8IW41 |
Catalog # | MBS2548840 |
Price | $110, $150, $225 |
Order / More Info | Phospho-PRAK (Thr182) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |