Human TNFRSF10D Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman TNFRSF10D
Clone[6G9]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS), Neutr
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DescriptionTNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. TRAIL binds at least five different receptors: TRAIL R1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAIL R1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAIL R1 and R2. TRAIL R3 is membrane-asso
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFRSF10D extracellular domain (also called TRAIL R4).
Other Names[TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4], [TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4]
Gene, Accession #[TNFRSF10D], Gene ID: 8793, NCBI: NP_003831.2, UniProt: Q9UBN6
Catalog #MBS690317
Price$490
Order / More InfoHuman TNFRSF10D Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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