Edit |   |
---|---|
Antigenic Specificity | HNF1B - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: 100% specific to all three isoforms of HNF1B (61, 58, 45kD). This is a rabbit polyclonal antibody against HNF1B. It was validated on Western BlotTarget Description: Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B |
Other Names | [Hepatocyte nuclear factor 1-beta; hepatocyte nuclear factor 1-beta; HNF1 homeobox B; Homeoprotein LFB3; Transcription factor 2; TCF-2; Variant hepatic nuclear factor 1] |
Gene, Accession # | [HNF1B], Gene ID: 6928, NCBI: NP_006472, UniProt: P35680 |
Catalog # | MBS3200859 |
Price | $365 |
Order / More Info | HNF1B - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |